Reduction of alkynes into 1,2-dideuterioalkenes with hexamethyldisilane and deuterium oxide in the presence of a palladium catalyst.

نویسندگان

  • Eiji Shirakawa
  • Hidehito Otsuka
  • Tamio Hayashi
چکیده

A combination of hexamethyldisilane and deuterium oxide was found to work as a deuterium transfer reagent for alkynes in the presence of a catalytic amount of a palladium complex to give (E)-1,2-dideuterioalkenes selectively through the corresponding (Z)-isomer.

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عنوان ژورنال:
  • Chemical communications

دوره 47  شماره 

صفحات  -

تاریخ انتشار 2005